OBTAINING A GENETIC ATTENUATED AROA MUTANT STRAIN PASTEURELLA MULTOCIDA
نویسندگان
چکیده
منابع مشابه
Pasteurella multocida P52 aroA mutant conferred protection to rabbits and mice against haemorrhagic septicaemia
Pasteurella multocida serotype B:2 is the etiological agent of haemorrhagic septicaemia (HS) in cattle and buffaloes, a disease that causes significant economic losses to the dairy industry in India. Several killed vaccines are in uses that provide protection to limited period of time. The aim of this study was to generate an attenuated strain of Pasteurella multocida P52 by targeted gene knock...
متن کاملUse of a Dual Reporter Plasmid to Demonstrate Bactofection with an Attenuated AroA- Derivative of Pasteurella multocida B:2
A reporter plasmid pSRG has been developed which expresses red fluorescent protein (RFP) from a constitutive prokaryotic promoter within Pasteurella multocida B:2 and green fluorescent protein (GFP) from a constitutive eukaryotic promoter within mammalian cells. This construct has been used to determine the location and viability of the bacteria when moving from the extracellular environment in...
متن کاملProtective immunity conferred by attenuated aroA derivatives of Pasteurella multocida B:2 strains in a mouse model of hemorrhagic septicemia.
Hemorrhagic septicemia (HS) is a fatal systemic disease of cattle and buffaloes. In South Asia HS is caused by infection with Pasteurella multocida serotype B:2. Some control is achieved with alum-precipitated or oil-adjuvanted killed whole-cell vaccines injected subcutaneously, but these vaccines provide only short-term immunity and require annual administration for effective use. Live attenua...
متن کاملGenome Sequence of Pasteurella multocida Strain Razi_Pm0001
We report here the genome sequence of Pasteurella multocida Razi_Pm0001 from bovine origin, isolated in Iran in 1936. The genome has a size of 2,360,663 bp, a G+C content of 40.4%, and is predicted to contain 2,052 coding sequences.
متن کاملDraft Genome Sequence of Pasteurella multocida subsp. multocida Strain PMTB, Isolated from a Buffalo
Pasteurella multocida serotypes B:2 and E:2 are the main causative agents of ruminant hemorrhagic septicemia in Asia and Africa, respectively. Pasteurella multocida strain PMTB was isolated from a buffalo with hemorrhagic septicemia and has been determined to be serotype B:2. Here we report the draft genome sequence of strain PMTB.
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ژورنال
عنوان ژورنال: International Journal of Applied and Fundamental Research (Международный журнал прикладных и фундаментальных исследований)
سال: 2020
ISSN: 1996-3955
DOI: 10.17513/mjpfi.13027